resources and further reading
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what is crispr-cas?
crispr-cas has made headlines as a powerful new gene editing tool that could change the whole of biology. find out more about what crispr is, how it works, and what it might be used for.
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archaea and crispr biology
the crispr-cas system is an adaptive immune system encoded in prokaryotes to defend against invasion of foreign genetic elements. archaeal organisms provide unique resources for investigations, to uncover the diversity and complexity of the immune system as this article in microbiology today explains.
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crispr-cas: from mechanism to applications
crispr-cas has been turned into a versatile genome editing method that has the potential to treat human genetic diseases. in this microbiology today article, we explore the architecture of crispr-cas and how crispr-cas9-based genome editing technology.
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microbiology and genetics
the genetic plasticity of microbes enables their survival. this microbiology today article outlines some of the advances that have been made in modern biotechnology and the significance of this research to microbiology.
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microbiology today: archaea
from extreme temperatures and highly acidic conditions to the insides of volcanoes and the depths of the ocean, a diverse group of microbes called archaea thrive in many places that most life can't survive. this issue of microbiology today highlights the importance of archaea and our current understanding of them.
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crispr journal collection
explore our journal collection dedicated to articles that focus on crispr.
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defra: the regulation of genetic technologies
the 英格兰vs美国谁会赢？ has submitted a response to the defra public consultation on the regulation of genetic technologies, which is assessing whether gene editing should be regulated in the same way as genetic modification, and is gathering views on the wider regulatory framework governing genetically modified organisms (gmos).
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crispr-cas and microbiology
the 2020 nobel prize in chemistry was awarded to professors emmanuelle charpentier and jennifer doudna for their work on the genetic editing tool crispr-cas9. in this blog, professor david grainger discusses some of the earliest research on crispr-cas9 published in our flagship journal microbiology.
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crispr-cas could hold the solution to amr
research carried out at the university of exeter has found a novel way to tackle the growing issue of antimicrobial resistance (amr) using the gene editing technology crispr-cas.
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discovery and development of next-generation crispr-cas tools
professor jennifer doudna was awarded the 英格兰vs美国谁会赢？ ’s prize medal in recognition for her fundamental work on crispr–cas systems – used by bacteria and archaea as adaptive immunity against foreign genetic elements such as viruses. in this blog, we revisit the lecture presented by dr christoff fellmann on professor doudna’s behalf.
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tackling antibiotic resistance the crispr way
this case study is written by david walker-sünderhauf, who is a phd student at the university of exeter and a member of the 英格兰vs美国谁会赢？ . it focuses on tackling antibiotic resistance using crispr-cas.
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resistance is (not) futile: bacterial innate and adaptive immune system
fleming prize winner, professor peter fineran gives a talk on his research around phage resistance systems, specifically crispr-cas and toxin-antitoxin/abortive infection systems.
image credits:
laguna design/science photo library
molekuul/science photo library
mcmurryjulie/pixabay
christoff fellmann
peter fineran
istock/panuwach
istock/molekuul
istock/vchal
